Revisiting endosulfan

Endosulfan and Endocrine Disruption:

Organochlorine ( Endosulfan) Poisoning

Pathology of Endosulfan

Endosulfan (6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro6,9-methano-2,4,3-benzo-odioxa-thiepin-3-oxide) is a chlorinated cyclodiene insecticide which acts as a contact poison in a wide variety of insects and mites (Naqvi and Vaishnavi, 1993). Endosulfan was first registered for use in the USA in 1954 to control agricultural insects and mite pests. Due to its toxic effect, the World Health O...

Endosulfan and black urine

This 21-year-old college student was admitted following alleged consumption of endosulfan 100 g along with alcohol 2 h earlier. He had had two episodes of generalized tonic clonic seizures which had been treated with lorazepam and phenytoin. At admission, he had tachycardia, tachypnoea and normal systemic examination. Fourteen hours after admission, his urobag revealed black urine (Figure 1). H...

Stereoselective degradation of aqueous endosulfan in modular estuarine mesocosms: formation of endosulfan gamma-hydroxycarboxylate.

Solutions of alpha-endosulfan, beta-endosulfan, and technical grade endosulfan (70alpha:30beta) were added to modular estuarine mesocosms; the kinetics and degradation products from each mesocosm are reported. The persistent product endosulfan sulfate was generated in all cases; however, its yield was approximately a factor of three higher from alpha-endosulfan relative to beta-endosulfan. Beta...